MyBioSource.com's AEBP1 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The AEBP1 Antibody was generated using AE Binding Protein 1, and AEBP1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Function: May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor.
Subunit Structure: Interacts with GNG5, NFKBIA, MAPK1, MAPK3 and PTEN. May interact with calmodulin. Binds to DNA in vitro.
Post-translational Modifications: Phosphorylated by MAPK1 in vitro.
Similarity: Belongs to the peptidase M14 family